#Benchmark180 #collected by Bradford and Westhead #Bradford JR, Westhead DR: Improved prediction of protein-protein binding sites using a support vector machines approach. Bioinformatics 2005, 21:1487-1494 Protein chains involved in non-obligate interactions ---------------------------------------------------- Enzyme-inhibitors: 1a4y_A ribonuclease inhibitor 1a4y_B angiogenin 1ava_A alpha amylase 1avw_A trypsin 1avw_B soybean trypsin inhibitor 1ay7_A ribonuclease Sa 1ay7_B Barstar 1bvn_T tendamistat 1clv_I alpha amylase inhibitor 1cse_I eglin C 1dpj_A proteinase A 1dpj_B proteinase inhibitor Ia3 1dtd_A carboxypeptidase A2 1dtd_B metallocarboxypeptidase inhibitor 1eai_C elastase/chymostrypsin inhibitor I 1f34_B major pepsin inhibitor 1fss_A acetylcholinesterase 1fss_B fasciculin II 1gla_F Glucose-Specific Factor III 1kxq_H antibody Vhh fragment 1mct_I squash seed inhibitor 1smp_A serratia metalloproteinase 1smp_I erwinia chysathemi inhibitor 1tab_I bowman-birk inhibitor 1tgs_I pancreatic secretory trypsin inhibitor 1udi_E uracil-DNA glycosylase 1udi_I UDG inhibitor 1viw_B alpha amylase inhibitor 2ptc_I bovine pancreatic trypsin inhibitor 2sic_E subtilisin BPN 2sic_I SSI 4cpa_I potato carboxypeptidase A inhibitor 4sgb_E serine proteinase B 4sgb_I potato chymotrypsin inhibitor I 7cei_A Im7 7cei_B DNAase Others: 1agr_E Rgs 4 1atn_D Deoxyribonuclease I 1b6c_A Fk506-Binding Protein 1b6c_B Tgf-B Superfamily Receptor Type I 1bkd_S Son Of Sevenless-1 1buh_B Cell cycle regulatory protein Ckshs1 1d2z_B Death Domain Of Tube 1dow_A alpha-catenin 1dow_B beta-catenin A 1eay_A chey 1eay_C chea 1euv_A Ulp1 Protease 1euv_B Ubitquitin-Like Protein Smt3 1f3v_B traf2 2.0A 1f5q_A Cyclin Dependent Kinase 2 1f5q_B Cyclin 1he1_A Exoenzyme S 1hx1_B Bag-Family Molecular Chaperone Regulator-1 1i2m_B Regulator Of Chromosome Condensation 1i8l_C Cytotoxic T-Lymphocyte Protein 4 1kac_B Adenovirus Receptor 1pdk_A Chaperone Protein Papd 1pdk_B Protein Papk 1qav_A alpha-1 Syntrophin 1tx4_A P50-Rhogap 1tx4_B Rhoa 1xdt_R Heparin-Binding Epidermal Growth Factor 1xdt_T Diphtheria Toxin 3ygs_C Apoptotic Protease Activating Factor 3ygs_P Procaspase 9 Protein chains involved in obligate interactions ------------------------------------------------ Hetero-dimers: 1ahj_A nitrite hydratase 1ahj_B nitrite hydratase 1aht_H alpha thrombin 1aht_L alpha thrombin 1b34_A Small Nuclear Ribonucleoprotein Sm 2 1b34_B Small Nuclear Ribonucleoprotein Sm 2 1bun_A beta-2-Bungarotoxin 1dce_A Rab Geranylgeranyltransferase 1dce_B Rab Geranylgeranyltransferase 1dj7_A ferredoxin thioredoxin 1efv_A electron transfer flavoprotein 1efv_B electron transfer flavoprotein 1g4y_B calcium-activated potassium channel Rsk 1g4y_R calmodulin 1gux_A Retinoblastoma Protein 1gux_B Retinoblastoma Protein 1h2a_L Ferricytochrome-C3 Oxidoreductase 1h2a_S Ferricytochrome-C3 Oxidoreductase 1luc_B Bacterial Luciferase 1pnk_A Penicillin Amidohydrolase 1pnk_B Penicillin Amidohydrolase 1req_A Methylmalonyl-Coa Mutase 1req_B Methylmalonyl-Coa Mutase 1tco_A serine/threonine phosphatase 2B 1tco_B serine/threonine phosphatase 2B 2aai_A ricin 2aai_B ricin Homo-dimers: 1a0f_B Glutathione S-Transferase 1a4i_A Methylenetetrahydrofolate Dehydrogenase 1a4u_A Alcohol Dehydrogenase 1afr_F delta-9 Stearoyl-Acyl Carrier Protein 1afw_A 3-Ketoacetyl-Coa Thiolase 1aj8_A Citrate Synthase 1ajs_A Aspartate Aminotransferase 1aom_A Nitrite Reductase 1aq6_A L-2-Haloacid Dehalogenase 1at3_A Herpes Simplex Virus Type II Protease 1az3_B Ecorv Endonuclease 1b3a_B Rantes 1b5e_A Deoxycytidylate Hydroxymethylase 1b7b_A Carbamate Kinase 1b8a_A Aspartyl-tRNA Synthetase 1b8j_B Alkaline Phosphatase 1b9m_B Molybdate-Dependent Transcriptional Regulator 1bbh_A cytochrome C 1bft_A Nuclear Factor Nf-kappa-B P65 1bjn_B Phosphoserine Aminotransferase 1bo1_A Phosphatidylinositol Phosphate Kinase 1brm_A Aspartate-Semialdehyde Dehydrogenase 1bw0_B Tyrosine Aminotransferase 1byf_A Polyandrocarpa lectin 1byk_B Trehalose Operon Repressor 1c7n_A Cystalysin 1cli_B Phosphoribosyl-Aminoimidazole Synthetase 1cmb_B Met Apo-Repressor (Metj) 1cnz_A 3-Isopropylmalate Dehydrogenase 1coz_A Glycerol-3-Phosphate Cytidylyltransferase 1cp2_A Nitrogenase Iron Protein 1dor_A Dihydroorotate Dehydrogenase A 1e0b_A Swi6 Protein 1ete_A Flt3 Ligand 1f5m_A Gaf 1f6y_A Iron Sulfur Protein Methyltransferase 1f8r_A L-Amino Acid Oxidase 1gpe_B Glucose Oxidase 1hgx_B Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase 1hjr_C RuvC resolvase 1hss_A 0.19 alpha-Amylase Inhibitor 1hul_A Interleukin-5 1isa_B Iron(II) Superoxide Dismutase 1jkm_A Brefeldin A Esterase 1kpe_A Protein Kinase C Interacting Protein 1mka_A beta-Hydroxydecanoyl Thiol Ester Dehydrogenase 1msp_A Major Sperm Protein 1nse_A Nitric Oxide Synthase 1nsy_A Nad Synthetase 1one_A Enolase 1pp2_L Phospholipase A2 1pvu_A Pvuii Restriction Endonuclease 1qae_B Extracellular Endonuclease 1qax_A 3-Hydroxy-3-Methylglutaryl-Coenzyme 1qbi_A Soluble Quinoprotein Glucose Dehydrogenase 1qfe_A 3-Dehydroquinate Dehydratase 1qfh_B Actin Binding Protein 120 1qi9_B Vanadium Bromoperoxidase 1qor_B Quinone Oxidoreductase 1qqj_A Fumarylacetoacetate Hydrolase 1qu7_B Methyl-Accepting Chemotaxis Protein 1scf_B Stem Cell Factor 1smt_A Transcriptional Repressor Smtb 1sox_A Sulfite Oxidase 1spu_A Copper Amine Oxidase 1trk_B Transketolase 1vfr_B Nad(P)H: Fmn Oxidoreductase 1vhi_A Epstein Barr Virus Nuclear Antigen-1 1vlt_A Aspartate Receptor 1vok_A Tata-Box-Binding Protein 1vsg_B Variant Surface Glycoprotein 1wgj_A Inorganic Pyrophosphatase 1xik_A Protein R2 Of Ribonucleotide Reductase 1xso_A Cu, Zn Superoxide Dismutase 1ypi_A Triose Phosphate Isomerase (TIM) 1yve_J Acetohydroxy Acid Isomeroreductase 2ae2_A Tropinone Reductase-II 2arc_A Arabinose Operon Regulatory Protein 2gsa_B Glutamate Semialdehyde Aminotransferase 2hdh_A L-3-Hydroxyacyl Coa Dehydrogenase 2hhm_B Inositol Monophosphatase 2nac_B Formate Dehydrogenase 2pfl_B Pyruvate Formate-Lyase 2utg_B Uteroglobin 3tmk_B Thymidylate Kinase 4mdh_A Cytoplasmic Malate Dehydrogenase 5hvp_B HIV-1 Protease